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Postdoctoral Fellow

Department: Wei
Location: Seattle, WA

The Wei Lab at the Institute for Systems Biology (ISB) is seeking highly-motivated postdoctoral candidates in the areas of cancer biology and translational cancer research.

The Wei Lab works in the highly cross-disciplinary field of molecular and cellular analysis, tumor epigenetics, and systems biomedicine. We develop and implement innovative single-cell/spatial multi-omics technologies with novel computational approaches to investigate the cutting-edge cancer biology questions with a balance between discovery and clinical translation. We are particularly interested in (1) the cause and consequence of tumor heterogeneity and the intricate cell-cell interactions in the tumor microenvironment for advancing cancer treatment; (2) tumor epigenetic plasticity/dysregulation and its contribution to the treatment-induced adaptive therapy resistance and adaptive mutagenesis; (3) liquid biopsy-based rare cell analysis for predictive cancer diagnostics and immunotherapy. The Wei lab is currently a part of the NIH-funded Cancer Systems Biology Consortium (CSBC), NIH-funded Physical Sciences in Oncology Network (PS-ON), and NIH-funded Innovative Molecular Analysis Technologies (IMAT) Program. Please visit for more information about the lab.

Candidates should have a Ph.D. in Biology, Computational Biology or Bioinformatics, Biological or Biomedical Engineering, Chemistry, or other related areas. They should have demonstrated the ability or potential to conduct interdisciplinary research with good communication skills and a strong publication record. Candidates with research experience in multi-omics/single-cell data analysis, machine-learning, and computational/systems biology are strongly preferred.

Exceptional candidates for this position may be nominated for the Lee Hood Systems Fellowship ( with an annual stipend of $95,000 over 2-3 years. These nominations are presented by the supporting Faculty member to the entire Faculty for approval. The postdoc candidate will be invited to submit additional information if they are nominated.

Interested applicants should submit their curriculum vitae and 1-page cover letter for a brief description of research interest through the online application portal and email a copy of their CV to

ISB is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.

Pay Range:

 ISB pays postdoctoral fellows on a scale based upon experience: $65,478 - $91,711 annually



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